In what began as shootout in Damascus, a local resident said he heard "gunfire at around 06:00 (03:00 GMT), then an explosion which smashed the glass of houses in the neighborhood".
Shortly there after officials say that a team of coordinated suicide bombers launched an attack in the Syrian capital of Damascus, with initial reports saying at least 19 people were killed and dozens of others face life threatening injuries.
Syrian Police Say they had been chasing three suspected car bombers that were trying to enter the capital, as announced on Syrian state television.
Police were able to stop and detonate two of the vehicles, but a third driver rammed through Tahrir square in the eastern entrance and blew himself up after being surrounded.
Syria is in the midst of a six-year-long civil war, with Damascus still mostly under government control. At least a few dozen people were injured and an estimated 20 were killed in Sunday's blast, reports said.
State TV announced that the attackers had premeditated a coordinated plan to bomb crowded areas with civilians in the capital on the first working day after the Muslim holy month of Ramadan.
"The terrorist bombings killed and wounded several civilians and caused physical damage to the area," said local police officials. The Syrian Foreign ministry sent an official letter to the United Nations announcing the attacks as well as condemning them.